Whiteley, A. E. et al. Leukaemia: A model metastatic disease. Nat. Rev. Cancer 21, 461–475 (2021).
Google Scholar
Jamalipour Soufi, G. et al. MXenes and MXene-based materials with cancer diagnostic applications: challenges and opportunities. Comments Inorganic Chem. 41(6), 1–34 (2021).
Selvakumari, D. et al. Anti cancer activity of ZnO nanoparticles on MCF7 (breast cancer cell) and A549 (lung cancer cell). ARPN J. Eng. Appl. Sci 10(12), 5418–5421 (2015).
Duan, X. et al. Zinc oxide nanoparticles synthesized from Cardiospermum halicacabum and its anticancer activity in human melanoma cells (A375) through the modulation of apoptosis pathway. J. Photochem. Photobiol. B Biol. 202, 111718 (2020).
Trayes, K. P. & Cokenakes, S. E. Breast cancer treatment. Am. Fam. Physician 104(2), 171–178 (2021).
Google Scholar
Hamidian, K. et al. Doped and un-doped cerium oxide nanoparticles: Biosynthesis, characterization, and cytotoxic study. Ceramics Int. 47(10, Part A), 13895–13902 (2021).
Google Scholar
Haghighat, M. et al. Cytotoxicity properties of plant-mediated synthesized K-doped ZnO nanostructures. Bioprocess Biosyst. Eng. 45(1), 1–8 (2022).
Cheng, Z. et al. Nanomaterials for cancer therapy: Current progress and perspectives. J. Hematol. Oncol. 14(1), 1–27 (2021).
Sartaj, A., Baboota, S. & Ali, J. Assessment of combination approaches of phytoconstituents with chemotherapy for the treatment of breast cancer, a systematic review. Curr. Pharm. Des. 27(45), 4630–4648 (2021).
Liu, H. et al. Detention of copper by sulfur nanoparticles inhibits the proliferation of A375 malignant melanoma and MCF-7 breast cancer cells. Biochem. Biophys. Res. Commun. 477(4), 1031–1037 (2016).
Google Scholar
Mukhtar, M. et al. Application of nanotechnology for sensitive detection of low-abundance single-nucleotide variations in genomic DNA: A review. Nanomaterials 11(6), 1384 (2021).
Google Scholar
Barani, M. et al. Evaluation of carum-loaded niosomes on breast cancer cells: Physicochemical properties, in vitro cytotoxicity, flow cytometric, DNA fragmentation and cell migration assay. Sci. Rep. 9(1), 1–10 (2019).
Google Scholar
Wang, Y. & Wang, F. Post-translational modifications of deubiquitinating enzymes: Expanding the ubiquitin code. Front. Pharmacol. 12, 1434 (2021).
Sun, S. et al. BP4RNAseq: A babysitter package for retrospective and newly generated RNA-seq data analyses using both alignment-based and alignment-free quantification method. Bioinformatics 37(9), 1319–1321 (2021).
Google Scholar
Rahdar, A. et al. Biochemical, ameliorative and cytotoxic effects of newly synthesized curcumin microemulsions: Evidence from in vitro and in vivo studies. Nanomaterials 11(3), 817 (2021).
Google Scholar
Torkzadeh-Mahani, M. et al. A combined theoretical and experimental study to improve the thermal stability of recombinant d-lactate dehydrogenase immobilized on a novel superparamagnetic Fe3O4NPs@metal–organic framework. Appl. Organometallic Chem. 34(5), e5581 (2020).
Google Scholar
Sabir, F. et al. DNA based and stimuli-responsive smart nanocarrier for diagnosis and treatment of cancer: Applications and challenges. Cancers 13(14), 3396 (2021).
Google Scholar
Hajizadeh, M. R. et al. In vitro cytotoxicity assay of d-limonene niosomes: An efficient nano-carrier for enhancing solubility of plant-extracted agents. Res. Pharm. Sci. 14(5), 448 (2019).
Google Scholar
Barani, M. et al. Lawsone-loaded niosome and its antitumor activity in MCF-7 breast cancer cell line: A nano-herbal treatment for cancer. DARU J. Pharm. Sci. 26, 11–17 (2018).
Google Scholar
Barani, M. et al. Nanodiagnosis and nanotreatment of colorectal cancer: An overview. J. Nanopart. Res. 23(1), 1–25 (2021).
Google Scholar
Barani, M. et al. Nanotreatment and nanodiagnosis of prostate cancer: Recent updates. Nanomaterials 10(9), 1696 (2020).
Google Scholar
Barani, M. et al. Simulation, in vitro, and in vivo cytotoxicity assessments of methotrexate-loaded pH-responsive nanocarriers. Polymers 13(18), 3153 (2021).
Google Scholar
Barani, M. et al. Progress in the application of nanoparticles and graphene as drug carriers and on the diagnosis of brain infections. Molecules 26(1), 186 (2021).
Google Scholar
Xiao, J.-H. & Zhong, J.-J. Secondary metabolites from Cordyceps species and their antitumor activity studies. Recent Pat. Biotechnol. 1(2), 123–137 (2007).
Google Scholar
Ji, X. et al. Structural characterization of polysaccharide from jujube (Ziziphus jujuba Mill.) fruit. Chem. Biol. Technol. Agric. 8(1), 1–7 (2021).
Ji, X. et al. Metagenomic analysis of gut microbiota modulatory effects of jujube (Ziziphus jujuba Mill.) polysaccharides in a colorectal cancer mouse model. Food Funct. 11(1), 163–173 (2020).
Google Scholar
Pimentel-Moral, S. et al. Lipid nanocarriers for the loading of polyphenols—A comprehensive review. Adv. Colloid Interface. Sci. 260, 85–94 (2018).
Google Scholar
da Volta Soares, M. et al. Nanostructured delivery system for zinc phthalocyanine: Preparation, characterization, and phototoxicity study against human lung adenocarcinoma A549 cells. Int. J. Nanomed. 6, 227 (2011).
Li, L. et al. Simulation of the in vivo fate of polymeric nanoparticles traced by environment-responsive near-infrared dye: A physiologically based pharmacokinetic modelling approach. Molecules 26(5), 1271 (2021).
Google Scholar
Kostiv, U. et al. Monodisperse core-shell NaYF4:Yb3+/Er3+@NaYF4:Nd3+-PEG-GGGRGDSGGGY-NH2 nanoparticles excitable at 808 and 980 nm: Design, surface engineering, and application in life sciences. Front. Chem. 8, 497 (2020).
Google Scholar
Kostiv, U. et al. Physico-chemical characteristics, biocompatibility, and MRI applicability of novel monodisperse PEG-modified magnetic Fe3O4&SiO2 core–shell nanoparticles. RSC Adv. 7(15), 8786–8797 (2017).
Google Scholar
Cao, Y. et al. K-doped ZnO nanostructures: Biosynthesis and parasiticidal application. J. Mater. Res. Technol. 15, 5445–5451 (2021).
Google Scholar
Sabir, F. et al. Nanodiagnosis and nanotreatment of cardiovascular diseases: An overview. Chemosensors 9(4), 67 (2021).
Google Scholar
Amiri, M. S. et al. Plant-based gums and mucilages applications in pharmacology and nanomedicine: A review. Molecules 26(6), 1770 (2021).
Google Scholar
Alijani, H. Q. et al. Biosynthesis of spinel nickel ferrite nanowhiskers and their biomedical applications. Sci. Rep. 11(1), 17431 (2021).
Google Scholar
Barani, M. et al. A new formulation of hydrophobin-coated niosome as a drug carrier to cancer cells. Mater. Sci. Eng. C 113, 110975 (2020).
Google Scholar
Kouhbanani, M. A. J. et al. The inhibitory role of synthesized nickel oxide nanoparticles against Hep-G2, MCF-7, and HT-29 cell lines: The inhibitory role of NiO NPs against Hep-G2, MCF-7, and HT-29 cell lines. Green Chem. Lett. Rev. 14(3), 443–453 (2021).
Google Scholar
Rahdar, A. et al. Deferasirox-loaded pluronic nanomicelles: Synthesis, characterization, in vitro and in vivo studies. J. Mol. Liq. 323, 114605 (2021).
Google Scholar
Sargazi, S. et al. F127/cisplatin microemulsions: In vitro, in vivo and computational studies. Appl. Sci. 11(7), 3006 (2021).
Google Scholar
Cao, Y. et al. Ceramic magnetic ferrite nanoribbons: Eco-friendly synthesis and their antifungal and parasiticidal activity. Ceramics Int. 48, 1–7 (2021).
Reshmy, R. et al. Nanobiocatalysts: advancements and applications in enzyme technology. Bioresour. Technol. 337, 125491 (2021).
Google Scholar
Alijani, H. Q. et al. Biosynthesis of spinel nickel ferrite nanowhiskers and their biomedical applications. Sci. Rep. 11(1), 1–7 (2021).
Rahdar, A. et al. Behavioral effects of zinc oxide nanoparticles on the brain of rats. Inorga. Chem. Commun. 119, 1–14 (2020).
Khatami, M. et al. Waste-grass-mediated green synthesis of silver nanoparticles and evaluation of their anticancer, antifungal and antibacterial activity. Green Chem. Lett. Rev. 11(2), 125–134 (2018).
Google Scholar
Nazari-Vanani, R. et al. A novel self-nanoemulsifying formulation for sunitinib: Evaluation of anticancer efficacy. Colloids Surf. B Biointerfaces 160, 65–72 (2017).
Google Scholar
Lomelí-Marroquín, D. et al. Starch-mediated synthesis of mono-and bimetallic silver/gold nanoparticles as antimicrobial and anticancer agents. Int. J. Nanomed. 14, 2171 (2019).
Ghosh, S. et al. Novel platinum–palladium bimetallic nanoparticles synthesized by Dioscorea bulbifera: Anticancer and antioxidant activities. Int. J. Nanomed. 10, 7477 (2015).
Google Scholar
Elemike, E. E. et al. Green synthesis of Ag, Au and Ag-Au bimetallic nanoparticles using Stigmaphyllon ovatum leaf extract and their in vitro anticancer potential. Mater. Lett. 243, 148–152 (2019).
Google Scholar
Trommenschlager, A. et al. Gold (i)–BODIPY–imidazole bimetallic complexes as new potential anti-inflammatory and anticancer trackable agents. Dalton Trans. 46(25), 8051–8056 (2017).
Google Scholar
Sivamaruthi, B. S. et al. Biogenic synthesis of silver palladium bimetallic nanoparticles from fruit extract of Terminalia chebula—In vitro evaluation of anticancer and antimicrobial activity. J. Drug Deliv. Sci. Technol. 51, 139–151 (2019).
Google Scholar
Dobrucka, R. et al. Evaluation of biologically synthesized Au-CuO and CuO-ZnO nanoparticles against glioma cells and microorganisms. Saudi Pharm. J. 27(3), 373–383 (2019).
Google Scholar
Elemike, E. E., Onwudiwe, D. C. & Singh, M. Eco-friendly synthesis of copper oxide, zinc oxide and copper oxide–zinc oxide nanocomposites, and their anticancer applications. J. Inorg. Organomet. Polym Mater. 30(2), 400–409 (2020).
Google Scholar
Rajeshkumar, S. et al. Biosynthesis of zinc oxide nanoparticles using Mangifera indica leaves and evaluation of their antioxidant and cytotoxic properties in lung cancer (A549) cells. Enzyme Microb. Technol. 117, 91–95 (2018).
Google Scholar
Kalaiarasi, A. et al. Copper oxide nanoparticles induce anticancer activity in A549 lung cancer cells by inhibition of histone deacetylase. Biotechnol. Lett. 40(2), 249–256 (2018).
Google Scholar
Chakraborty, R. & Basu, T. Metallic copper nanoparticles induce apoptosis in a human skin melanoma A-375 cell line. Nanotechnology 28(10), 105101 (2017).
Google Scholar
Hussein, B. Y. & Mohammed, A. M. Green synthesis of ZnO nanoparticles in grape extract: Their application as anti-cancer and anti-bacterial. Mater. Today Proc. 42(3), 18–26 (2021).
Ahamed, M. et al. Genotoxic potential of copper oxide nanoparticles in human lung epithelial cells. Biochem. Biophys. Res. Commun. 396(2), 578–583 (2010).
Google Scholar
Mota, A. H. et al. Green extraction of Sambucus nigra L. for potential application in skin nanocarriers. Green Mater. 8(4), 181–193 (2020).
Fang, J. & Xuan, Y. Investigation of optical absorption and photothermal conversion characteristics of binary CuO/ZnO nanofluids. RSC Adv. 7(88), 56023–56033 (2017).
Google Scholar
Wasim, M. et al. Surface modification of bacterial cellulose by copper and zinc oxide sputter coating for UV-resistance/antistatic/antibacterial characteristics. Coatings 10(4), 364 (2020).
Google Scholar
Khatami, M. et al. Rectangular shaped zinc oxide nanoparticles: Green synthesis by Stevia and its biomedical efficiency. Ceram. Int. 44(13), 15596–15602 (2018).
Google Scholar
Zowczak, M. et al. Analysis of serum copper and zinc concentrations in cancer patients. Biol. Trace Elem. Res. 82(1), 1–8 (2001).
Google Scholar
Soetan, K., Olaiya, C. & Oyewole, O. The importance of mineral elements for humans, domestic animals and plants—A review. Afr. J. Food Sci. 4(5), 200–222 (2010).
Google Scholar
Ros-Bullon, M., Sanchez-Pedreno, P. & Martinez-Liarte, J. Serum zinc levels are increased in melanoma patients. Melanoma Res. 8(3), 273–277 (1998).
Google Scholar
Zarghami, N. et al. Correlation between serum levels of zinc and copper and telomerase gene expression in lung cancer patients. Pharma. Sci. 14(4), 183–190 (2009).

