SARS-CoV-2 RNA is highly structured in host cells To study the secondary structures of SARS-CoV-2 RNAs inside cells, we infected Vero-E6 cells with WT and Δ382 SARS-CoV-2 and performed structure…
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Elaborately designed DNA icosahedral shells cage intact virions to effectively protect host cells from viral infections. Emerging and re-emerging viral diseases present significant threats to public health, as witnessed by…
DNA is much more than the genetic information it carries. It is a versatile material for creating systems with tailor-made functionalities that are having an important impact in emerging technologies.…
1. Pollard, A. J. & Bijker, E. M. A guide to vaccinology: from basic principles to new developments. Nat. Rev. Immunol. 21, 83–100 (2021). CAS PubMed Article PubMed Central Google…
Large scale SC experiments are in increasing demand but choosing the correct WGA technology may not be derived by true comparisons of kits as such comparison is costly and laborious.…
A team of researchers at Massachusetts General Hospital (MGH), Boston University School of Public Health (BUSPH), and other institutions have identified more than two dozen genetic regions that may affect…
The old adage “never let them see you sweat,” doesn’t apply in the electrical and computer engineering lab of Rose Faghih, assistant professor of electrical and computer engineering in the…
Previous research has shown that the spike (S) protein of -CoV-2 binds to a host cell receptor, facilitating viral entry. Research has also shown that SARS-CoV-2 variants that lose the…
An enzyme with an elusive role in severe inflammation may be a key mechanism driving COVID-19 severity and could provide a new therapeutic target to reduce COVID-19 mortality, according to…
