Compact RNA editors with small Cas13 proteins
1. Terns, M. P. CRISPR-based technologies: impact of RNA-targeting systems. Mol. Cell 72, 404–412 (2018). CAS Article Google Scholar 2. Cox, D. B. T. et al. RNA editing with CRISPR-Cas13.…
Whole genome sequencing of clinical samples reveals extensively drug resistant tuberculosis (XDR TB) strains from the Beijing lineage in Nigeria, West Africa
Sample collection, DNA extraction and Molecular drug resistance assay Random sputum samples (n = 10) that were collected in the month of July, 2019 from patients who were referred for diagnosis at…
Molecular-dynamics-simulation-guided membrane engineering allows the increase of membrane fatty acid chain length in Saccharomyces cerevisiae
Very long-chain glycerophospholipids increase the rigidity of in silico membranes in a concentration-dependent manner MD simulations were used to investigate how increasing the concentrations of very-long-chain FA GPLs affect the…
Photobiomodulation as an antioxidant substitute in post-thawing trauma of human stem cells from the apical papilla
Cell culture and cryopreservation SCAP at a passage of 3–5 were used in this experiment. SCAP were isolated from a human tooth. We obtained Institutional Review Board approval at Seoul…
Research Into “Achilles Heel” of Cancer Tumors Paves Way for New Treatment Strategies
Researchers at the University of British Columbia’s faculty of medicine and BC Cancer Research Institute have uncovered a weakness in a key enzyme that solid tumor cancer cells rely on…
Delta Variant Is 60% More Contagious Than Original COVID Virus and Can Escape Immunity
The Delta variant is more contagious than original SARS-CoV-2 and better able to escape prior immunity, according to modeling studies of coronavirus variants. Researchers at Columbia University Mailman School of…
DNA From Modern Human Buried 7,000 Years Ago Shows Previously Unknown Ancient Human Relations
The Leang Panninge cave on the southern peninsula of Sulawesi, Indonesia. Credit: Leang Panninge Research Project International research team isolates DNA from modern human buried 7,000 years ago on the…
Global Warming Simulation Reveals Possible End of El Niño/ La Niña Temperature Cycle
Surface ocean temperatures simulated at unprecedented resolution using a coupled atmosphere-ocean model. The extensive wavy cold structure in the equatorial Pacific corresponds to a tropical instability wave. Simulations were conducted…
How NASA Takes Notes in Space
NASA astronaut Walter Cunningham writes with a Fisher Space Pen during the flight of Apollo 7, the first crewed Apollo flight and the Space Pen’s first trip to space. The…
New Simulation Reveals How Galaxies Feed Their Supermassive Black Holes
A still image from the simulation showing a large region containing tens of galaxies (6 million light-years across). Credit: Anglés-Alcázar et al. 2021, ApJ, 917, 53 First model to show…
