Preloader

Biovalorization of raw agro-industrial waste through a bioprocess development platform for boosting alkaline phosphatase production by Lysinibacillus sp. strain APSO

Isolation and identification of ALP-producing bacteria In the preliminary exploration, the growth of the bacterial microflora of a slime sample from Alexandria paper and pulp factory was enriched in a…

Efficient CRISPR editing with a hypercompact Cas12f1 and engineered guide RNAs delivered by adeno-associated virus

Overall strategy for gRNA engineering Efforts to engineer gRNAs have contributed to improving CRISPR tools with respect to efficiency of indel generation27, simplicity4, multiplexing28, imaging29 and specificity4,30. To optimize the…

Multiple strain analysis of Streptomyces species from Philippine marine sediments reveals intraspecies heterogeneity in antibiotic activities

Isolation of marine sediment-derived actinomycetes from west-central Philippines The geographical sites identified in this study were evaluated to explore the actinomycete distribution in west-central Philippines (Fig. 1a). A total of 16…

On-target IgG hexamerisation driven by a C-terminal IgM tail-piece fusion variant confers augmented complement activation

1. Casak, S. J. et al. U.S. Food and drug administration approval: rituximab in combination with fludarabine and cyclophosphamide for the treatment of patients with chronic lymphocytic leukemia. oncologist 16,…

Intensive monitoring of minimal residual disease and chimerism after allogeneic hematopoietic stem cell transplantation for acute leukemia in children

1. Hunger SP, Mullighan CG. Acute lymphoblastic leukemia in children. N Engl J Med. 2015;373:1541–52. CAS  PubMed  Article  PubMed Central  Google Scholar  2. Schrappe M, Hunger SP, Pui C-H, Saha…