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Pacific Northwest Wildfires Alter Air Pollution Patterns Across North America – Posing Potential Health Risks to Millions of People

According to recent research, larger and more intense wildfires in the Pacific Northwest are changing the seasonal rhythm of air pollution and triggering an increase in hazardous pollutants in August.…

Chimeric bacteriocin S5-PmnH engineered by domain swapping efficiently controls Pseudomonas aeruginosa infection in murine keratitis and lung models

Identification of Pseudomonas putative pore-forming bacteriocin sequences Putative pore-forming bacteriocins from genus Pseudomonas have been retrieved from NCBI by BLAST search using as query pore-forming domain of pyocin S5 (pfam01024).…

Development of NanoLuc-targeting protein degraders and a universal reporter system to benchmark tag-targeted degradation platforms

Development of NanoTACs; a NanoLuc-targeting degrader system We developed heterobifunctional degraders that bind NanoLuc (NanoTACs) to trigger protein degradation of NanoLuc-tagged substrates building upon the existing tTPD systems that direct…