The Center for Devices and Radiological Health, US Food and Drug Administration, Silver Spring, MD, USA
Wenming Xiao & Zivana Tezak
State Key Laboratory of Genetic Engineering, Human Phenome Institute, School of Life Sciences and Shanghai Cancer Center, Fudan University, Shanghai, China
Luyao Ren, Yuanting Zheng, Ying Yu & Leming Shi
Center for Genomics, Loma Linda University School of Medicine, Loma Linda, CA, USA
Zhong Chen, Wanqiu Chen, Xin Chen & Charles Wang
Bioinformatics Research & Early Development, Roche Sequencing Solutions Inc., Belmont, CA, USA
Li Tai Fang
Advanced Biomedical and Computational Sciences, Biomedical Informatics and Data Science Directorate, Frederick National Laboratory for Cancer Research, Frederick, MD, USA
Yongmei Zhao, Justin Lack, Ashley Walton, Tsai-Wei Shen, Keyur Talsania & Cristobal Juan Vera
SAS Institute Inc., Cary, NC, USA
Meijian Guan
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Rockville, MD, USA
Bin Zhu
Illumina Inc., Foster City, CA, USA
Erich Jaeger, Ogan D. Abaan, Tiffany Truong, Ali Moshrefi, Aparna Natarajan, Ana Granat & Gary P. Schroth
ATCC, Manassas, VA, USA
Liz Kerrigan, Kurt Langenbach & Maryellen de Mars
Departments of Medicine and Pathology, University of Toledo Medical Center, Toledo, OH, USA
Thomas M. Blomquist, Jennifer A. Hipp & James C. Willey
Genentech, South San Francisco, CA, USA
Tiffany Hung, Rasika Kalamegham & Eric Peters
Biomarker Development, Novartis Institutes for Biomedical Research, Basel, Switzerland
Marc Sultan & Virginie Petitjean
Computational Genomics, Genomics Research Center, AbbVie, North Chicago, IL, USA
Kenneth Idler, Charles Lu, Chris Miller & Howard Jacob
Institute for Molecular Medicine Finland, University of Helsinki, Helsinki, Finland
Andreas Scherer
European Infrastructure for Translational Medicine, Amsterdam, the Netherlands
Andreas Scherer, Jessica Nordlund, Ulrika Liljedahl, Roberta Maestro, Maurizio Polano, Jiri Drabek, Petr Vojta, Sulev Kõks & Ene Reimann
Immuneering Corporation, Cambridge, MA, USA
Rebecca Kusko
The Center for Biologics Evaluation and Research, US Food and Drug Administration, Silver Spring, MD, USA
Malcolm Moos
National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, MD, USA
Chunlin Xiao & Stephen T. Sherry
Seven Bridges Genomics Inc., Cambridge, MA, USA
Ogan D. Abaan
Department of Medical Sciences, Molecular Medicine and Science for Life Laboratory, Uppsala University, Uppsala, Sweden
Jessica Nordlund
Centro di Riferimento Oncologico di Aviano IRCCS, National Cancer Institute, Unit of Oncogenetics and Functional Oncogenomics, Aviano, Italy
Ulrika Liljedahl, Roberta Maestro & Maurizio Polano
IMTM, Faculty of Medicine and Dentistry, Palacky University Olomouc, Olomouc, Czech Republic
Jiri Drabek & Petr Vojta
Perron Institute for Neurological and Translational Science, Nedlands, Perth, Western Australia, Australia
Sulev Kõks
Centre for Molecular Medicine and Innovative Therapeutics, Murdoch University, Murdoch, Perth, Western Australia, Australia
Sulev Kõks
Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia
Ene Reimann
Garvan Institute of Medical Research, The Kinghorn Cancer Centre, Darlinghurst, New South Wales, Australia
Bindu Swapna Madala & Timothy Mercer
National Institute of Metrology, Beijing, China
Jing Wang
Sequencing Facility, Cancer Research Technology Program, Frederick National Laboratory for Cancer Research, Frederick, MD, USA
Jyoti Shetty, Yuliya Kriga, Arati Raziuddin & Bao Tran
CCR Collaborative Bioinformatics Resource, Office of Science and Technology Resources, Center for Cancer Research, Bethesda, MD, USA
Margaret Cam & Parthav Jailwala
Computational Genomics and Bioinformatics Branch, Center for Biomedical Informatics and Information Technology, National Cancer Institute, Rockville, MD, USA
Cu Nguyen, Daoud Meerzaman, Qingrong Chen & Chunhua Yan
Digicon, McLean, VA, USA
Ben Ernest & Urvashi Mehra
Department of Biological Sciences, Virginia Polytechnic Institute and State University, Blacksburg, VA, USA
Roderick V. Jensen
Q2 Solutions–EA Genomics, Morrisville, NC, USA
Wendell Jones
Integrative Bioinformatics, National Institute of Environmental Health Sciences, Durham, NC, USA
Jian-Liang Li & Brian N. Papas
Bioinformatics and Computational Biology Core, National Heart Lung and Blood Institute, National Institutes of Health, Bethesda, MD, USA
Mehdi Pirooznia, Yun-Ching Chen & Fayaz Seifuddin
Sentieon Inc., Mountain View, CA, USA
Zhipan Li
Center for Information Technology, National Institutes of Health, Bethesda, MD, USA
Xuelu Liu & Wolfgang Resch
AstraZeneca, Gaithersburg, MD, USA
Jingya Wang
National Center for Toxicological Research, US Food and Drug Administration, Jefferson, AR, USA
Leihong Wu, Gokhan Yavas, Corey Miles, Baitang Ning, Weida Tong & Huixiao Hong
Department of Physiology and Biophysics, Weill Cornell Medicine, New York, NY, USA
Christopher E. Mason
The Center for Drug Evaluation and Research, US Food and Drug Administration, Silver Spring, MD, USA
Eric Donaldson
Office of the Chief Scientist, Office of the Commissioner, US Food and Drug Information, Silver Spring, MD, USA
Samir Lababidi
Lymphoid Malignancies Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA
Louis M. Staudt
The study was conceived and designed by W.X., L.S., E.D., S.L., L.M.S. and Z.T. Biosample preparation was performed by T.M.B., J.A.H., L.K., K.L., M.M. and J.C.W. NGS library preparation and sequencing were carried out by W.C., Z.C., J.D., A.G., T.H., K.I., H.J., E.J., R.K., B.S.M., S.K., Y.K., U.L., R.M., C.M., T.M., C. Miller, A.M., A.N., B.N., J.N., E.P., V.P., M. Polano, A.R., E.R., A.S, G.T.S., J.S., L.S., M.S., W.T., B.T., T.T., P.V., C.W., J.W. and Y. Zheng. Data analysis was performed by W.X., L.R., L.F., Y. Zhao, J.L., M.G., O.D.A., M.C., Q.C., X.C., Y.C., B.E., P.J., R.V.J., W.J., J.L., Z.L., X.L., C.L., D.M., U.M., C.M., C.N., B.N.P., M. Pirooznia, W.R., F.S., T.S., K.T., C.J.V., J.W., A.W., L.W., C.X., C.Y., G.Y., Y.Y. and B.Z. Data management was carried out by W.X., C.X., S.T.S., C.N. and D.M.. The manuscript was written by W.X., R.K., L.R., L.F., M.M., Y. Zhao and C.W. Project management was the responsibility of W.X., L.S., C.W., C.X. and H.H.
